Prof. Dr. rer. nat. Andrea Antal

Curriculum Vitae

Prof. Dr. rer. nat. Andrea Antal

Name

Andrea ANTAL

Nationality

German-Hungarian

Present work address

Department of Clinical Neurophysiology
University Medical Center
Georg-August University of Göttingen
Robert-Koch-Straße 40, 37075 Göttingen, Germany

Tel: 49-551-398461
Fax: 49-551-398126

E-mail: AAntal@gwdg.de

Profession

Biologist

Education and degrees

  • 2010 - Extraordinary professor, Georg-August University, Göttingen, Germany
  • 2005 - Habilitation, Georg-August University, Göttingen, Germany
  • 1998 – PhD, Albert Szent-Györgyi Medical University, Szeged, Hungary
  • 1993 - University Doctor, Attila József University of Sciences, Szeged, Hungary
  • 1990 - Diploma in Biology, Attila József University of Sciences, Szeged, Hungary

Present affiliation

Since 02/2001: Group leader, Georg-August University of Göttingen, Department of Clinical Neurophysiology; Göttingen, Germany

Former affiliations

11/1994 – 01/2001: Assistant Professor of Physiology, University of Szeged, Faculty of Medicine, Department of Physiology, Szeged, Hungary

7/1994 to 10/1994: Research Associate, State University of New York, Health Science Center at Brooklyn, Department of Neurology, New York, U.S.A.

7/1993 to 6/1994: Research Associate, University of Nebraska Medical Center, Department of Internal Medicine, Division of Neurology, Omaha, Nebraska U.S.A.

5/1991 - 8/1992: Research Assistant, Mount Sinai Medical Center, Department of Neurology, New York, U.S.A.

9/1990 - 5/1991 and 9/1992 - 6/1993: Research Assistant, József Attila University of Arts and Sciences, Department of Comparative Physiology, Szeged, Hungary

Selected publications

Antal A, Alekseichuk I, Bikson M, Brockmöller J, Brunoni AR, Chen R, Cohen LG, Dowthwaite G, Ellrich J, Flöel A, Fregni F, George MS, Hamilton R, Haueisen J, Herrmann CS, Hummel FC, Lefaucheur JP, Liebetanz D, Loo CK, McCaig CD, Miniussi C, Miranda PC, Moliadze V, Nitsche MA, Nowak R, Padberg F, Pascual-Leone A, Poppendieck W, Priori A, Rossi S, Rossini PM, Rothwell J, Rueger MA, Ruffini G, Schellhorn K, Siebner HR, Ugawa Y, Wexler A, Ziemann U, Hallett M, Paulus W. Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines. Clinical Neurophysiology, in press.

Turi Z, Mittner M, Paulus W, Antal A. Placebo Intervention Enhances Reward Learning in Healthy Individuals. Scientific Reports, 2017; 7:41028.

Alekseichuk I, Turi Z, de Lara G, Antal A, Paulus W. Spatial working memory in humans depends on theta and high gamma synchronization in prefrontal cortex. Current Biology, 2016, 26:1513-21.

Antal A, Herrmann CS. Transcranial alternating current and random noise stimulation: Possible mechanisms. Neural Plasticity, 2016: 3616807.

Alekseichuk I, Diers K, Paulus W, Antal A. Transcranial electrical stimulation of the occipital cortex during visual perception modifies the magnitude of BOLD activity: a combined tES-fMRI approach. Neuroimage, 2015, pii: S1053-8119(15)01056-3.

Turi Zs, Mittner M, Opitz A, Popkes M, Paulus W, Antal A. Transcranial direct current stimulation over the left prefrontal cortex increases randomness of choice in instrumental learning. Cortex, 2015; 63C:145-154.

Antal A, Bikson M, Datta A, Lafon B, Dechent P, Parra LC, Paulus W. Imaging artifacts induced by electrical stimulation during conventional fMRI of the brain. NeuroImage, 2014; 85:1040–1047.

Antal A, Kriener N, Lang N, Boros K, Paulus W. Cathodal transcranial direct current stimulation of the visual cortex in the prophylactic treatment of migraine, Cephalalgia, 2011, 31:820–28.

Antal A, Polania R, Schmidt-Samoa C, Dechent P, Paulus W. Transcranial direct current stimulation over the primary motor cortex during fMRI. NeuroImage, 2011;55:590-6.

Antal A, Chaieb L, Moliadze V, Monte-Silva K, Poreisz C, Thirugnanasambandam N, Nitsche MA, Shoukier M, Ludwig H, PaulusW. Brain-derived neurotrophic factor (BDNF) gene polymorphisms shape cortical plasticity in humans. Brain Stimulation, 2010, 3:230-237.

Academic performance

Number of scientific publications: ~ 245 + 16 book chapters
Cumulative impact factor: ~ 600
Number of scientific citations: ~ 8600 (without self-citation: ~7900)
H-Index: 45
last updated: August, 2017

Major Research Interests

Neuroplasticity became one central topic of neuroscience research in the last decades. Dynamic modifications of neuronal networks are an important substrate for learning and memory formation. Furthermore, pathological neuroplasticity might be one foundation of numerous central nervous system diseases.

The primary aim of our recent work is to develop and establish new non-invasive brain stimulation methods to induce physiological changes in the central nervous system in order to investigate cognition and complex information processing. Transcranial direct current stimulation (tDCS) was developed by our group as a non-invasive tool to induce neuroplasticity in the human cerebral cortex. tDCS as a tool aims to induce prolonged neuronal excitability and activity alterations in the human brain via alterations of the neuronal membrane potential. Accordingly, this method is a promising tool in the treatment of diseases that are accompanied by changes of cortical excitability. Transcranial alternating current stimulation (tACS) and random noise stimulation (tRNS) are new external stimulation techniques influencing cortical activity. tACS and tRNS permit, due to the oscillating stimulation, external interference with the cortical oscillations. They can particularly modulate the temporary connections of cortical areas during a given task. Neuronal oscillations in the brain are associated with the processing of sensory information, learning, cognition, arousal, attention and also pathological conditions (e.g. Parkinson's tremor, epilepsy). Therefore, the external modulation of cortical oscillations could be an important component of induced cerebral plasticity. In terms of effectiveness tRNS seems to have at least the same therapeutic potential for the treatment of diseases such as depression and chronic pain as rTMS and tDCS.